MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 130190 | Name: Phenothiazine 2a

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenothiazine 2a is an inhibitor of farnesyltransferase, showing promise for use in antitumor applications.

Chemical Structure

Phenothiazine 2a
Phenothiazine 2a
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130190

Name: Phenothiazine 2a

CAS#: N/A

Chemical Formula: C27H22N2O3S

Exact Mass: 454.1351

Molecular Weight: 454.54

Elemental Analysis: C, 71.35; H, 4.88; N, 6.16; O, 10.56; S, 7.05

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Phenothiazine 2a
IUPAC/Chemical Name
ethyl (E)-3-(3-(10-methyl-10H-phenothiazin-3-yl)acryloyl)indolizine-1-carboxylate
InChi Key
DEBGEDXBSMFDAS-WYMLVPIESA-N
InChi Code
InChI=1S/C27H22N2O3S/c1-3-32-27(31)19-17-23(29-15-7-6-8-20(19)29)24(30)14-12-18-11-13-22-26(16-18)33-25-10-5-4-9-21(25)28(22)2/h4-17H,3H2,1-2H3/b14-12+
SMILES Code
O=C(C1=C2C=CC=CN2C(C(/C=C/C3=CC=C4N(C)C5=C(C=CC=C5)SC4=C3)=O)=C1)OCC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 454.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Moise IM, Ghinet A, Belei D, Dubois J, Farce A, Bîcu E. New indolizine-chalcones as potent inhibitors of human farnesyltransferase: Design, synthesis and biological evaluation. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3730-4. doi: 10.1016/j.bmcl.2016.05.074. Epub 2016 May 26. PMID: 27282741.