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MedKoo Cat#: 130174 | Name: SGRM HP-19

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SGRM HP-19 is a selective glucocorticoid receptor modulator (SGRM) showing promise in the treatment of inflammatory and autoimmune disorders.

Chemical Structure

SGRM HP-19
SGRM HP-19
CAS#946246-96-4

Theoretical Analysis

MedKoo Cat#: 130174

Name: SGRM HP-19

CAS#: 946246-96-4

Chemical Formula: C23H24N2O5S

Exact Mass: 440.1406

Molecular Weight: 440.51

Elemental Analysis: C, 62.71; H, 5.49; N, 6.36; O, 18.16; S, 7.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SGRM HP-19; SGRM HP19; SGRM HP 19
IUPAC/Chemical Name
N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-2-methoxy-4,5-dimethylbenzenesulfonamide
InChi Key
NRMBLNSUKKPNMI-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H24N2O5S/c1-15-12-21(29-3)22(13-16(15)2)31(27,28)24-18-8-9-19-17(14-18)6-4-10-25(19)23(26)20-7-5-11-30-20/h5,7-9,11-14,24H,4,6,10H2,1-3H3
SMILES Code
O=S(C1=CC(C)=C(C)C=C1OC)(NC2=CC3=C(N(C(C4=CC=CO4)=O)CCC3)C=C2)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 440.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Li D, Bao X, Pang J, Hu X, Wang L, Wang J, Yang Z, Xu L, Wang S, Weng Q, Cui S, Hou T. Discovery and Optimization of N-Acyl-6-sulfonamide-tetrahydroquinoline Derivatives as Novel Non-Steroidal Selective Glucocorticoid Receptor Modulators. J Med Chem. 2022 Dec 8;65(23):15710-15724. doi: 10.1021/acs.jmedchem.2c01082. Epub 2022 Nov 18. PMID: 36399795.