SGRM B53, a selective glucocorticoid receptor modulator, has shown promise for use in the treatment of inflammatory and autoimmune disorders. SGRMs play a key role in dissociating the transactivation from the transrepression of the glucocorticoid receptor, with SGRM B53 being found to successfully reduce the expression of IL-6, IL-1β, and TNF-α.
MedKoo Cat#: 130173
Name: SGRM B53
CAS#: N/A
Chemical Formula: C24H23ClN2O4S
Exact Mass: 470.1067
Molecular Weight: 470.97
Elemental Analysis: C, 61.21; H, 4.92; Cl, 7.53; N, 5.95; O, 13.59; S, 6.81
The following data is based on the product molecular weight 470.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
