SGC-PIKFYVE-1 is a PIKfyve inhibitor and functions as a cell-active chemical probe. SGC-PIKFYVE-1 has been shown to disrupt viral replication and viral entry of the β-coronavirus lifecycle. Furthermore, unlike most kinase inhibitors, SGC-PIKFYVE-1 lacks the canonical morpholine hinge-binder
MedKoo Cat#: 130125
Name: SGC-PIKFYVE-1
CAS#: 2857982-26-2
Chemical Formula: C20H21N5
Exact Mass: 331.1797
Molecular Weight: 331.42
Elemental Analysis: C, 72.48; H, 6.39; N, 21.13
The following data is based on the product molecular weight 331.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
