RTI122 is a GPR88 agonist with IC50=11 nM). RTI-122 was more effective than RTI-13951-33 in attenuating the binge-like alcohol drinking behavior in the drinking-in-the-dark paradigm. RTI-122 is a promising lead compound for drug discovery research of GPR88 agonists
MedKoo Cat#: 122725
Name: RTI-122
CAS#: 3034664-39-3
Chemical Formula: C29H34FN3O3
Exact Mass: 491.2600
Molecular Weight: 491.61
Elemental Analysis: C, 70.85; H, 6.97; F, 3.86; N, 8.55; O, 9.76
The following data is based on the product molecular weight 491.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
