MedKoo Cat#: 130085 | Name: HM41322

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HM41322 is a SGLT1/2 dual inhibitor and was shown to maximize the amount of glucose excreted through the urine. HM41322 shows promise as an agent for postprandial glucose control.

Chemical Structure

HM41322
HM41322
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130085

Name: HM41322

CAS#: N/A

Chemical Formula: C24H30O5

Exact Mass: 398.2093

Molecular Weight: 398.50

Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 72.34; H, 7.59; O, 20.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
HM41322
IUPAC/Chemical Name
(2S,3R,4R,5S,6R)-2-[7-(4-Ethylbenzyl)-2,3-dihydro-1H-inden-5-yl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChi Key
OVFHLFVDLPPVNL-SJSRKZJXSA-N
InChi Code
InChI=1S/C24H30O5/c1-2-14-6-8-15(9-7-14)10-17-12-18(11-16-4-3-5-19(16)17)24-23(28)22(27)21(26)20(13-25)29-24/h6-9,11-12,20-28H,2-5,10,13H2,1H3/t20-,21-,22+,23-,24+/m1/s1
SMILES Code
O[C@H]1[C@H](C2=CC3=C(CCC3)C(CC4=CC=C(CC)C=C4)=C2)O[C@H](CO)[C@@H](O)[C@@H]1O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 398.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Lee KH, Lee SD, Kim N, Suh KH, Kim YH, Sim SS. Pharmacological evaluation of HM41322, a novel SGLT1/2 dual inhibitor, in vitro and in vivo. Korean J Physiol Pharmacol. 2019 Jan;23(1):55-62. doi: 10.4196/kjpp.2019.23.1.55. Epub 2018 Dec 26. PMID: 30627010; PMCID: PMC6315097.