PQM-181 is an AChE inhibitor for the treatment of Alzheimer's disease. PQM-181 has displayed antioxidant activity against neuronal t-BOOH-induced oxidative stress, demonstrated neuroprotective ability against neurotoxicity elicited by both t-BOOH and OAβ1-42, as well as a has been shown to have a moderate ability to interfere with Aβ1-42 aggregates.
MedKoo Cat#: 130074
Name: PQM-181
CAS#: N/A
Chemical Formula: C21H25N3O3
Exact Mass: 367.1896
Molecular Weight: 367.45
Elemental Analysis: C, 68.64; H, 6.86; N, 11.44; O, 13.06
The following data is based on the product molecular weight 367.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |