CDD-1431 | CAS# | potent | BMPR2 | inhibitor

MedKoo Cat#: 122679 | Name: CDD-1431

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CDD-1431 is a potent and BMPR2-selective kinase inhibitor

Chemical Structure

CDD-1431

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 122679

Name: CDD-1431

CAS#: N/A

Chemical Formula: C33H38N8O5S

Exact Mass: 658.2700

Molecular Weight: 658.78

Elemental Analysis: C, 60.17; H, 5.81; N, 17.01; O, 12.14; S, 4.87

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CDD-1431; CDD1431; CDD 1431

IUPAC/Chemical Name

N-(3-(4-(5-methoxy-2-((3-sulfamoylphenyl)amino)pyrimidin-4-yl)piperazin-1-yl)benzyl)-4-(3-(methylamino)-3-oxopropyl)benzamide

InChi Key

HSNLCCKRVCPONE-UHFFFAOYSA-N

InChi Code

InChI=1S/C33H38N8O5S/c1-35-30(42)14-11-23-9-12-25(13-10-23)32(43)36-21-24-5-3-7-27(19-24)40-15-17-41(18-16-40)31-29(46-2)22-37-33(39-31)38-26-6-4-8-28(20-26)47(34,44)45/h3-10,12-13,19-20,22H,11,14-18,21H2,1-2H3,(H,35,42)(H,36,43)(H2,34,44,45)(H,37,38,39)

SMILES Code

COC(C=N1)=C(N2CCN(C3=CC(CNC(C4=CC=C(CCC(NC)=O)C=C4)=O)=CC=C3)CC2)N=C1NC5=CC=CC(S(N)(=O)=O)=C5

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 658.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Modukuri RK, Monsivais D, Li F, Palaniappan M, Bohren KM, Tan Z, Ku AF, Wang Y, Madasu C, Li JY, Tang S, Miklossy G, Palmer SS, Young DW, Matzuk MM. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. J Med Chem. 2023 Jan 31. doi: 10.1021/acs.jmedchem.2c01886. Epub ahead of print. PMID: 36719862.