Cy7 bis-NHS ester is a bifunctional near-infrared (NIR) fluorescent dye derivative that features two N-hydroxysuccinimide (NHS) ester groups, enabling efficient and stable conjugation to primary amines on biomolecules such as antibodies, peptides, or proteins. It retains the optical properties of Cy7 dyes, with maximal absorption around 750 nm and emission near 770–780 nm, providing strong signal and low background in in vivo and ex vivo imaging applications. The dual NHS ester functionality allows for multi-site labeling or crosslinking, making it especially valuable in bioconjugation, diagnostics, and targeted imaging.
MedKoo Cat#: 122620
Name: Cy7 bis-NHS ester
CAS#: 2183440-71-1
Chemical Formula: C50H58ClN4O8+
Exact Mass: 877.3900
Molecular Weight: 878.48
Elemental Analysis: C, 68.36; H, 6.66; Cl, 4.04; N, 6.38; O, 14.57
The following data is based on the product molecular weight 878.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
