Avibactam tomilopil is an oral beta-lactamase inhibitor with antibacterial properties. It is a prodrug of Avibactam, which is the first beta-lactamase inhibitor of the diazabicyclooctanes class. Avibactam prevents beta-lactamase enzymes that are produced by microorganisms from destroying beta-lactam antibiotics. Avibactam tomilopil has potential to address the growing crisis of antibiotic resistance and has already been shown to be effective against M. abscessus pulmonary disease in mouse models.
MedKoo Cat#: 130019
Name: Avibactam tomilopil
CAS#: 2245880-46-8
Chemical Formula: C14H23N3O8S
Exact Mass: 393.1206
Molecular Weight: 393.41
Elemental Analysis: C, 42.74; H, 5.89; N, 10.68; O, 32.53; S, 8.15
The following data is based on the product molecular weight 393.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
