Inh2-B1 is an inhibitor of STK1, also known as Ser/Thr protein kinase. Inh2-B1 functions by directly binding to the ATP-binding catalytic domain of STK1. STK1 is a vital constituent of cell wall biosynthesis in Staphylococcus aureus and is responsible for MRSA's drug resistance. Inh2-B1 serves as a “antibiotic-resistance-breaker,” due to its ability to prevent biofilm formation.
MedKoo Cat#: 130012
Name: Inh2-B1
CAS#: 690216-38-7
Chemical Formula: C19H13N3O4S2
Exact Mass: 411.0347
Molecular Weight: 411.45
Elemental Analysis: C, 55.46; H, 3.18; N, 10.21; O, 15.55; S, 15.58
The following data is based on the product molecular weight 411.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
