MedKoo Cat#: 130010 | Name: 15-crown-5-PEG2-Haloligand

Description:

WARNING: This product is for research use only, not for human or veterinary use.

15-crown-5-PEG2-Haloligand is a chemigenetic sodium ion indicator created through the use of a crown-ether-containing ligand and has been noted, as opposed to using fully protein-based indicators, to increase specificity during imaging of biological systems. Furthermore, 15-crown-5-PEG2-Haloligand is an example of the development of bright and sensitive indicators for use in cell imaging.

Chemical Structure

15-crown-5-PEG2-Haloligand
15-crown-5-PEG2-Haloligand
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130010

Name: 15-crown-5-PEG2-Haloligand

CAS#: N/A

Chemical Formula: C26H42ClNO9

Exact Mass: 547.2548

Molecular Weight: 548.07

Elemental Analysis: C, 56.98; H, 7.72; Cl, 6.47; N, 2.56; O, 26.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
15-crown-5-PEG2-Haloligand; 15 crown 5 PEG2 Haloligand
IUPAC/Chemical Name
2-(2-(2-((6-Chlorohexyl)oxy)ethoxy)ethoxy)-N-(2,3,5,6,8,9,11,12-octahydrobenzo[b][1,4,7,10,13]pentaoxacyclopentadecin-15-yl)acetamide
InChi Key
XWVAOAKYFPTSGV-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H42ClNO9/c27-7-3-1-2-4-8-30-9-10-32-15-16-35-22-26(29)28-23-5-6-24-25(21-23)37-20-18-34-14-12-31-11-13-33-17-19-36-24/h5-6,21H,1-4,7-20,22H2,(H,28,29)
SMILES Code
O=C(NC1=CC=C2OCCOCCOCCOCCOC2=C1)COCCOCCOCCCCCCCl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 548.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Zhu W, Takeuchi S, Imai S, Terada T, Ueda T, Nasu Y, Terai T, Campbell RE. Chemigenetic indicators based on synthetic chelators and green fluorescent protein. Nat Chem Biol. 2023 Jan;19(1):38-44. doi: 10.1038/s41589-022-01134-z. Epub 2022 Sep 22. PMID: 36138142.