MedKoo Cat#: 122557 | Name: FCL55088
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

2'-Deoxyuridine 5'-monophosphate disodium salt is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate.

Chemical Structure

FCL55088
FCL55088
CAS#42155-08-8

Theoretical Analysis

MedKoo Cat#: 122557

Name: FCL55088

CAS#: 42155-08-8

Chemical Formula: C9H11N2Na2O8P

Exact Mass: 352.0000

Molecular Weight: 352.15

Elemental Analysis: C, 30.70; H, 3.15; N, 7.96; Na, 13.06; O, 36.35; P, 8.80

Price and Availability

Size Price Availability Quantity
250mg USD 350.00 2 Weeks
500mg USD 600.00 2 Weeks
1g USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
Disodium 2'-deoxyuridylate; 2'-Deoxyuridine 5'-monophosphate disodium salt; 5'-Uridylic acid, 2'-deoxy-, disodium salt; 6AG9V4748N; FCL55088; FCL 55088; FCL-55088
IUPAC/Chemical Name
sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate
InChi Key
FXVXMLXAXVVONE-CDNBRZBRSA-L
InChi Code
InChI=1S/C9H13N2O8P.2Na/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17);;/q;2*+1/p-2/t5-,6+,8+;;/m0../s1
SMILES Code
O[C@@H](C[C@H](N1C(NC(C=C1)=O)=O)O2)[C@H]2COP([O-])([O-])=O.[Na+].[Na+]
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 352.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Funk RS, van Haandel L, Becker ML, Leeder JS. Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line. J Pharmacol Exp Ther. 2013 Oct;347(1):154-63. doi: 10.1124/jpet.113.206672. Epub 2013 Jul 25. PMID: 23887097; PMCID: PMC3781408.