V-125 is a synthetic rexinoid that acts as an agonist of retinoid X receptors (RXRs), promoting RXR homodimerization with high potency. Preclinical studies have shown its effectiveness in reducing tumor growth in breast and lung cancer models. It also demonstrates a favorable toxicity profile, avoiding the triglyceride elevation commonly observed with other rexinoids.
MedKoo Cat#: 471214
Name: V-125
CAS#: 1807740-94-8
Chemical Formula: C23H30N2O2
Exact Mass: 366.2300
Molecular Weight: 366.51
Elemental Analysis: C, 75.37; H, 8.25; N, 7.64; O, 8.73
The following data is based on the product molecular weight 366.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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