3'-O-Methyladenosine | CAS#10300-22-8 | Lipid | Nucleosides

MedKoo Cat#: 122528 | Name: 3'-O-Methyladenosine

Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

3'-O-Methyladenosine

Chemical Structure

3'-O-Methyladenosine

CAS#10300-22-8

Theoretical Analysis

MedKoo Cat#: 122528

Name: 3'-O-Methyladenosine

CAS#: 10300-22-8

Chemical Formula: C11H15N5O4

Exact Mass: 281.1100

Molecular Weight: 281.27

Elemental Analysis: C, 46.97; H, 5.38; N, 24.90; O, 22.75

Price and Availability

Size	Price	Availability
100mg	USD 250.00	2 Weeks
250mg	USD 450.00	2 Weeks
500mg	USD 750.00	2 Weeks
1g	USD 1,250.00	2 Weeks

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

3'-O-Methyladenosine; 10300-22-8; 3'-o-methyl-d-adenosine; Adenosine, 3'-O-methyl-; 3'-O-methyl-Adenosine

IUPAC/Chemical Name

(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol

InChi Key

RYAFZRROCNNRFK-IOSLPCCCSA-N

InChi Code

InChI=1S/C11H15N5O4/c1-19-8-5(2-17)20-11(7(8)18)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1

SMILES Code

OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)N)O1)O)OC

Appearance

To be determined

Purity

>97% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 281.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Yano J, Kan LS, Ts'o PO. A simple method of the preparation of 2'-O-methyladenosine. Methylation of adenosine with methyl iodide in anhydrous alkaline medium. Biochim Biophys Acta. 1980 Apr 17;629(1):178-83. doi: 10.1016/0304-4165(80)90276-7. PMID: 7370305. 2: Hecht SM, Hawrelak SD, Kozarich JW, Schmidt FJ, Bock RM. Chemical modifications of transfer RNA species. Transfer RNA's terminating in 2'- and 3'-O-methyladenosine. Biochem Biophys Res Commun. 1973 Jun 19;52(4):1341-7. doi: 10.1016/0006-291x(73)90648-7. PMID: 4577827. 3: Chinault AC, Kozarich JW, Hecht SM, Schmidt FJ, Bock RM. Preparation of Escherichia coli tRNAs terminating of modified nucleosides by the use of CTP(ATP):tRNA nucleotidyltransferase and polynucleotide phosphorylase. Biochemistry. 1977 Feb 22;16(4):756-65. doi: 10.1021/bi00623a030. PMID: 319825. 4: Smee DF, Sidwell RW. Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides. Nucleosides Nucleotides Nucleic Acids. 2004;23(1-2):375-83. doi: 10.1081/ncn-120028334. PMID: 15043161.