MedKoo Cat#: 122516 | Name: WZ1831

Description:

WARNING: This product is for research use only, not for human or veterinary use.

WZ1831 is a Highly Selective Inhibitor of the Human Constitutive Proteasome β5c Chymotryptic Subunit. WZ1831 enters the cells to engage the proteasome target, potently and selectively kills multiple myeloma cells, and does so by synergizing with a β5i-selective inhibitor.

Chemical Structure

WZ1831
WZ1831
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 122516

Name: WZ1831

CAS#: N/A

Chemical Formula: C25H29BN4O6

Exact Mass: 492.2200

Molecular Weight: 492.34

Elemental Analysis: C, 60.99; H, 5.94; B, 2.20; N, 11.38; O, 19.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
WZ1831; WZ-1831; WZ 1831
IUPAC/Chemical Name
(S)-(3-((2-(2-(1H-indol-3-yl)-2-oxoacetamido)-4-(tert-butylamino)-4-oxobutanamido)methyl)phenyl)boronic acid
InChi Key
ATSWPXLAIPHFLB-FQEVSTJZSA-N
InChi Code
InChI=1S/C25H29BN4O6/c1-25(2,3)30-21(31)12-20(23(33)28-13-15-7-6-8-16(11-15)26(35)36)29-24(34)22(32)18-14-27-19-10-5-4-9-17(18)19/h4-11,14,20,27,35-36H,12-13H2,1-3H3,(H,28,33)(H,29,34)(H,30,31)/t20-/m0/s1
SMILES Code
O=C(NCC1=CC(B(O)O)=CC=C1)[C@@H](NC(C(C2=CNC3=C2C=CC=C3)=O)=O)CC(NC(C)(C)C)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 492.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL