MedKoo Cat#: 122499 | Name: 2'-Deoxyuridine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

2'-Deoxyuridine has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death.

Chemical Structure

2'-Deoxyuridine
2'-Deoxyuridine
CAS#951-78-0

Theoretical Analysis

MedKoo Cat#: 122499

Name: 2'-Deoxyuridine

CAS#: 951-78-0

Chemical Formula: C9H12N2O5

Exact Mass: 228.0746

Molecular Weight: 228.20

Elemental Analysis: C, 47.37; H, 5.30; N, 12.28; O, 35.05

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
10g USD 350.00 2 Weeks
25g USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
2'-DEOXYURIDINE; 951-78-0; deoxyuridine; Uracil deoxyriboside; Uridine, 2'-deoxy-
IUPAC/Chemical Name
1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChi Key
MXHRCPNRJAMMIM-SHYZEUOFSA-N
InChi Code
InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1
SMILES Code
OC[C@@H]1[C@H](C[C@H](N2C(NC(C=C2)=O)=O)O1)O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 228.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chenna A, Iden CR. Characterization of 2'-deoxycytidine and 2'-deoxyuridine adducts formed in reactions with acrolein and 2-bromoacrolein. Chem Res Toxicol. 1993 May-Jun;6(3):261-8. doi: 10.1021/tx00033a003. PMID: 8318647. 2: Michalska L, Wawrzyniak D, Szymańska-Michalak A, Barciszewski J, Boryski J, Baraniak D. Synthesis and biological assay of new 2'-deoxyuridine dimers containing a 1,2,3-triazole linker. Part I. Nucleosides Nucleotides Nucleic Acids. 2019;38(3):218-235. doi: 10.1080/15257770.2018.1514122. Epub 2018 Dec 27. PMID: 30588866. 3: Mori S, Morihiro K, Obika S. C5-azobenzene-substituted 2'-deoxyuridine- containing oligodeoxynucleotides for photo-switching hybridization. Molecules. 2014 Apr 22;19(4):5109-18. doi: 10.3390/molecules19045109. PMID: 24759071; PMCID: PMC6271114.