2'-Fluoro-2'-Deoxyguanosine | CAS#78842-13-4 | Nucleosides

MedKoo Cat#: 122477 | Name: 2'-Fluoro-2'-Deoxyguanosine

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

2'-Fluoro-2'-Deoxyguanosine

Chemical Structure

2'-Fluoro-2'-Deoxyguanosine

CAS#78842-13-4

Theoretical Analysis

MedKoo Cat#: 122477

Name: 2'-Fluoro-2'-Deoxyguanosine

CAS#: 78842-13-4

Chemical Formula: C10H12FN5O4

Exact Mass: 285.0873

Molecular Weight: 285.24

Elemental Analysis: C, 42.11; H, 4.24; F, 6.66; N, 24.55; O, 22.44

Price and Availability

Size	Price	Availability
1g	USD 350.00	2 Weeks
2g	USD 550.00	2 Weeks
5g	USD 1,050.00	2 Weeks

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Related CAS #

No Data

Synonym

78842-13-4; 2'-Deoxy-2'-fluoroguanosine; 2'-Fluoro-2'-deoxyguanosine; 2'-Fluoro -2'-deoxyguanosine; 2-Fluoro -2-deoxyguanosine

IUPAC/Chemical Name

2-amino-9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one

InChi Key

UXUZARPLRQRNNX-DXTOWSMRSA-N

InChi Code

InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s1

SMILES Code

O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C2N=C(N)NC3=O)[C@@H]1F

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 285.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Meneghesso S, Vanderlinden E, Brancale A, Balzarini J, Naesens L, McGuigan C. Synthesis and biological evaluation of purine 2'-fluoro-2'-deoxyriboside ProTides as anti-influenza virus agents. ChemMedChem. 2013 Mar;8(3):415-25. doi: 10.1002/cmdc.201200562. Epub 2013 Feb 5. PMID: 23386468. 2: Gohda K, Matsuo N, Oda Y, Ikehara M, Uesugi S. Effects of 2'-substituents of the first deoxyguanosine residue in the recognition sequence of EcoRI restriction endonuclease activity. J Biochem. 1997 Feb;121(2):219-24. PMID: 9089393.