MedKoo Cat#: 122322 | Name: Oleic-DBCO
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oleic-DBCO linker is a novel tool to conjugate lipid to azide-tagged biomolecules. Lipid modification changes the pharmacokinetics of the bioconjugate and prolongs its half-life in the circulation. DBCO reacts with azide bearing biomolecule through a copper-free click reaction instantly and in high yield.

Chemical Structure

Oleic-DBCO
Oleic-DBCO
CAS#2279951-78-7

Theoretical Analysis

MedKoo Cat#: 122322

Name: Oleic-DBCO

CAS#: 2279951-78-7

Chemical Formula: C36H48N2O2

Exact Mass: 540.3716

Molecular Weight: 540.79

Elemental Analysis: C, 79.96; H, 8.95; N, 5.18; O, 5.92

Price and Availability

Size Price Availability Quantity
50mg USD 550.00 2 Weeks
100mg USD 900.00 2 Weeks
250mg USD 1,400.00 2 Weeks
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Related CAS #
No Data
Synonym
Oleic-DBCO; 2279951-78-7; BP-24249; HY-141293; CS-0115940
IUPAC/Chemical Name
(Z)-N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]octadec-9-enamide
InChi Key
XQWJKAQVIAJNTR-KTKRTIGZSA-N
InChi Code
InChI=1S/C36H48N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25-35(39)37-29-28-36(40)38-30-33-23-18-17-21-31(33)26-27-32-22-19-20-24-34(32)38/h9-10,17-24H,2-8,11-16,25,28-30H2,1H3,(H,37,39)/b10-9-
SMILES Code
CCCCCCCC/C=C\CCCCCCCC(NCCC(N1CC(C=CC=C2)=C2C#CC3=C1C=CC=C3)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 540.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Meghani, N. M., Amin, H. H., Park, C., Park, J. B., Cui, J. H., Cao, Q. R., & Lee, B. J. (2018). Design and evaluation of clickable gelatin-oleic nanoparticles using fattigation-platform for cancer therapy. International Journal of Pharmaceutics, 545(1-2), 101-112. Taiariol, L., Chaix, C., Farre, C., & Moreau, E. (2021). Click and bioorthogonal chemistry: the future of active targeting of nanoparticles for nanomedicines?. Chemical Reviews, 122(1), 340-384.