BP Lipid 221 is an ionizable amino lipid which has both ester bonds located adjacent to C7 relative to the nitogen amine. This lipid is an analogous to BP-25498/ALC-0315. The head contains butanolamine which can efficiently encapsulate mRNA. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile.
MedKoo Cat#: 122309
Name: BP Lipid 221
CAS#: N/A
Chemical Formula: C50H99NO5
Exact Mass: 793.7523
Molecular Weight: 794.34
Elemental Analysis: C, 75.60; H, 12.56; N, 1.76; O, 10.07
The following data is based on the product molecular weight 794.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
