BP Lipid 149 is an ionizable amine lipid with propanolamine head which can efficiently encapsulate mRNA. Ester linkages are incorporated in the structure at C8 adn C6 position relative to amine. These introduction of ester bonds can increase tissue clearance of the lipid in the liver. The primary ester at C8 poisition has a 7-carbons lipid tail. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle.
MedKoo Cat#: 122297
Name: BP Lipid 149
CAS#: N/A
Chemical Formula: C41H81NO5
Exact Mass: 667.6115
Molecular Weight: 668.10
Elemental Analysis: C, 73.71; H, 12.22; N, 2.10; O, 11.97
The following data is based on the product molecular weight 668.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
