BP Lipid 130 is an ionizable amine lipid analogous to SM-102. The propanolamine head improves encapsulation of mRNA. The lipid has both esters at C6 position relative to the amine nitrogen. Ester linkages in the lipid tails are introduced into the structure to improve tissue clearance. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle.
MedKoo Cat#: 122278
Name: BP Lipid 130
CAS#: N/A
Chemical Formula: C43H85NO5
Exact Mass: 695.6428
Molecular Weight: 696.16
Elemental Analysis: C, 74.19; H, 12.31; N, 2.01; O, 11.49
The following data is based on the product molecular weight 696.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
