BP Lipid 126 is an amino ionizable lipid with ester bonds located at C8 and C7 position relative to nitrogen. The ester linkages are introduced to improve tissue clearance. The ethanolamine head can effectively enhance mRNA encapsulation. The primary ester at C8 position contains 9 carbons lipid tail. The ionizable lipid can be used for mRNA delivery due to its excellent physiochemical properties.
MedKoo Cat#: 122269
Name: BP Lipid 126
CAS#: 2157489-64-8
Chemical Formula: C43H85NO5
Exact Mass: 695.6428
Molecular Weight: 696.16
Elemental Analysis: C, 74.19; H, 12.31; N, 2.01; O, 11.49
The following data is based on the product molecular weight 696.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
