BP Lipid 116 is an ionizable amine lipid with ethanolamine head which can efficiently encapsulate mRNA. Ester linkages are incorporated, at C7 adn C6 position relative to amine, in the structure to increase tissue clearance of the lipid in the liver. The primary ester has a 7-carbons lipid tail. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle.
MedKoo Cat#: 122259
Name: BP Lipid 116
CAS#: N/A
Chemical Formula: C39H77NO5
Exact Mass: 639.5802
Molecular Weight: 640.05
Elemental Analysis: C, 73.19; H, 12.13; N, 2.19; O, 12.50
The following data is based on the product molecular weight 640.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
