BP Lipid 103 is an amine ionizable lipid analogous to SM-102. The ethanolamine head improves encapsulation of mRNA. The lipid has both esters at C6 position relative to the amine nitrogen. Ester linkages in the lipid tails are introduced into the structure to improve tissue clearance. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle.
MedKoo Cat#: 122248
Name: BP Lipid 103
CAS#: 2714482-36-5
Chemical Formula: C42H83NO5
Exact Mass: 681.6271
Molecular Weight: 682.13
Elemental Analysis: C, 73.95; H, 12.27; N, 2.05; O, 11.73
The following data is based on the product molecular weight 682.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
