MedKoo Cat#: 122233 | Name: GL67
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GL67 is a cationic lipid composed of cholesterol coupled to spermine. GL67 may be used to mediate gene transfer into mammalian cells. This lipid was a critical component for successfully completed clinical studies in the delivery of pDNA via inhalation.

Chemical Structure

GL67
GL67
CAS# 179075-30-0

Theoretical Analysis

MedKoo Cat#: 122233

Name: GL67

CAS#: 179075-30-0

Chemical Formula: C38H70N4O2

Exact Mass: 614.5499

Molecular Weight: 615.00

Elemental Analysis: C, 74.21; H, 11.47; N, 9.11; O, 5.20

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
GL67; GL 67 GL-67; N4-Spermine cholesterol carbamate
IUPAC/Chemical Name
(3S,10R,13R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (3-aminopropyl)(4-((3-aminopropyl)amino)butyl)carbamate
InChi Key
KBBLYWGVXTZWCU-FWAFJIPTSA-N
InChi Code
InChI=1S/C38H70N4O2/c1-28(2)11-8-12-29(3)33-15-16-34-32-14-13-30-27-31(17-19-37(30,4)35(32)18-20-38(33,34)5)44-36(43)42(26-10-22-40)25-7-6-23-41-24-9-21-39/h13,28-29,31-35,41H,6-12,14-27,39-40H2,1-5H3/t29-,31+,32?,33-,34?,35?,37+,38-/m1/s1
SMILES Code
NCCCNCCCCN(CCCN)C(O[C@@H]1CC2=CCC(C(CC[C@@H]3[C@H](C)CCCC(C)C)[C@]3(C)CC4)C4[C@@]2(C)CC1)=O
Appearance
To be determined
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 615.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL