Thalidomide-5-(C6-amine) is a PROTAC building block that contains an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS ester group or carboxylic acid in the presence of EDC or HATU.
MedKoo Cat#: 122200
Name: Thalidomide-5-(C6-amine)
CAS#: 2496687-00-2
Chemical Formula: C20H24N4O5
Exact Mass: 400.1747
Molecular Weight: 400.44
Elemental Analysis: C, 59.99; H, 6.04; N, 13.99; O, 19.98
The following data is based on the product molecular weight 400.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
