MedKoo Cat#: 556159 | Name: CVN03650
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CVN03650, also known as IL-17 modulator 4, is an IL-17 modulator. This compound was first reported in Journal of Medicinal Chemistry (2022), 65(13), 8828-8842 (Compound 23). This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

CVN03650
CVN03650
CAS#2446803-65-0

Theoretical Analysis

MedKoo Cat#: 556159

Name: CVN03650

CAS#: 2446803-65-0

Chemical Formula: C27H34N6O2

Exact Mass: 474.2743

Molecular Weight: 474.61

Elemental Analysis: C, 68.33; H, 7.22; N, 17.71; O, 6.74

Price and Availability

Size Price Availability Quantity
100mg USD 3,850.00 2 Weeks
200mg USD 6,450.00 2 Weeks
1g USD 12,950.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
IL-17 modulator 4; CVN03650; CVN 03650; CVN-03650;
IUPAC/Chemical Name
1H-Pyrazole-5-carboxamide, N-[(1S)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)-
InChi Key
CQKVACARDGYEMU-VWLOTQADSA-N
InChi Code
InChI=1S/C27H34N6O2/c1-15(2)33-22(13-14-28-33)26(34)30-25(24(19-5-6-19)20-7-8-20)27(35)29-21-11-9-18(10-12-21)23-16(3)31-32-17(23)4/h9-15,19-20,24-25H,5-8H2,1-4H3,(H,29,35)(H,30,34)(H,31,32)/t25-/m0/s1
SMILES Code
O=C(C1=CC=NN1C(C)C)N[C@H](C(NC2=CC=C(C3=C(C)NN=C3C)C=C2)=O)C(C4CC4)C5CC5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Journal of Medicinal Chemistry (2022), 65(13), 8828-8842

Preparing Stock Solutions

The following data is based on the product molecular weight 474.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Kevin Neil Dack, et al. Amino-acid anilides as small molecule modulators of il-17. WO2020127685A1. https://patents.google.com/patent/WO2020127685A1/ 2. Zhang B, Dömling A. Small molecule modulators of IL-17A/IL-17RA: a patent review (2013-2021). Expert Opin Ther Pat. 2022 Nov;32(11):1161-1173. doi: 10.1080/13543776.2022.2143264. Epub 2022 Nov 9. PMID: 36350977.