(S,R,S)-VL285 Phenol is a ProTAC building block. (S,R,S)-VL285 Phenol is used in the recruitment of the von Hippel-Lindau (VHL) protein for targeted protein degradation, providing an alternative to the widely used VH032. (S,R,S)-VL285 Phenol-linekr conjugates are also available for synthesis of degraders.
MedKoo Cat#: 121227
Name: (S,R,S)-VL285 Phenol
CAS#: 1448188-69-9
Chemical Formula: C29H32N4O5S
Exact Mass: 548.2093
Molecular Weight: 548.66
Elemental Analysis: C, 63.49; H, 5.88; N, 10.21; O, 14.58; S, 5.84
The following data is based on the product molecular weight 548.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
