9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
nonanoic Acid5544.jpg "9-(Boc-amino)nonanoic Acid")
MedKoo Cat#: 122135
Name: 9-(Boc-amino)nonanoic Acid
CAS#: 173435-78-4
Chemical Formula: C14H27NO4
Exact Mass: 273.1940
Molecular Weight: 273.37
Elemental Analysis: C, 61.51; H, 9.96; N, 5.12; O, 23.41
The following data is based on the product molecular weight 273.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
