tert-Butyl (10-aminodecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. tert-Butyl (10-aminodecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
MedKoo Cat#: 122117
Name: tert-Butyl (10-aminodecyl)carbamate
CAS#: 216961-61-4
Chemical Formula: C15H32N2O2
Exact Mass: 272.2464
Molecular Weight: 272.43
Elemental Analysis: C, 66.13; H, 11.84; N, 10.28; O, 11.75
The following data is based on the product molecular weight 272.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |