9-Aminononanoic acid can be used as a PROTAC linker and other conjugation in the synthesis of PROTACs. 9-Aminononanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
MedKoo Cat#: 122105
Name: 9-Aminononanoic acid
CAS#: 1120-12-3
Chemical Formula: C9H19NO2
Exact Mass: 173.1416
Molecular Weight: 173.26
Elemental Analysis: C, 62.39; H, 11.05; N, 8.08; O, 18.47
The following data is based on the product molecular weight 173.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
