A new class of thiol-specific conjugation reagents consisting of a thiol-reactive 3-arylpropiolonitrile (APN) group, with good stability in aqueous media. The APN group allows the targeted coupling of thiols in biomolecules, and results in stable thioether linkages without the risk of subsequent side reactions that can occur with maleimides.
MedKoo Cat#: 122064
Name: APN-C3-PEG5-acid
CAS#: N/A
Chemical Formula: C27H37N3O9
Exact Mass: 547.2530
Molecular Weight: 547.61
Elemental Analysis: C, 59.22; H, 6.81; N, 7.67; O, 26.29
The following data is based on the product molecular weight 547.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
