endo-BCN-Val-cit-PAB-MMAE is a synthetic antibody drug conjugate coupled to an BCN group. It contains a a protease-sensitive Val-Cit dipeptide, and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells. The BCN group can react with azide -tagged compound or biomolecules.
MedKoo Cat#: 122015
Name: endo-BCN-Val-Cit-PAB-MMAE
CAS#: 2474773-53-8
Chemical Formula: C69H106N10O14
Exact Mass: 1298.7890
Molecular Weight: 1299.66
Elemental Analysis: C, 63.77; H, 8.22; N, 10.78; O, 17.23
The following data is based on the product molecular weight 1,299.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
