PVN00595 is a ProTAC building block. PVN00595 enables the synthesis of molecules for targeted protein degradation. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand and an alkyl-chain crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 121176
Name: PVN00595
CAS#: Unknown
Chemical Formula: C29H43ClN4O5S
Exact Mass: 594.2643
Molecular Weight: 595.20
Elemental Analysis: C, 58.52; H, 7.28; Cl, 5.96; N, 9.41; O, 13.44; S, 5.39
The following data is based on the product molecular weight 595.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
