MedKoo Cat#: 121165 | Name: YZN76760
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

YZN76760 is a ProTAC building block. YZN76760 contains a von Hippel-Lindau (VHL)-recruting ligand, a rigid linker, and a pendant phosphoramidite for reactivity with target DNA-binding proteins such as transcription factors. This product has no formal name at the moment. For the convenience of communication, a temporal code was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

YZN76760
YZN76760
CAS#2828476-76-0

Theoretical Analysis

MedKoo Cat#: 121165

Name: YZN76760

CAS#: 2828476-76-0

Chemical Formula: C39H59N6O7PS

Exact Mass: 786.3904

Molecular Weight: 786.97

Elemental Analysis: C, 59.52; H, 7.56; N, 10.68; O, 14.23; P, 3.94; S, 4.07

Price and Availability

Size Price Availability Quantity
50mg USD 685.00 2 Weeks
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Related CAS #
No Data
Synonym
(S,R,S)-AHPC-C5-phosphoramidite
IUPAC/Chemical Name
(3R,5S)-1-((2S)-2-(6-(((2-Cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexanamido)-3,3-dimethylbutanoyl)-5-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-3-yl acetate
InChi Key
YMQQWUSOVSQPIT-ZGBSLLNRSA-N
InChi Code
InChI=1S/C39H59N6O7PS/c1-26(2)45(27(3)4)53(51-21-13-19-40)50-20-12-10-11-14-34(47)43-36(39(7,8)9)38(49)44-24-32(52-29(6)46)22-33(44)37(48)41-23-30-15-17-31(18-16-30)35-28(5)42-25-54-35/h15-18,25-27,32-33,36H,10-14,20-24H2,1-9H3,(H,41,48)(H,43,47)/t32-,33+,36-,53?/m1/s1
SMILES Code
CC(O[C@H]1CN(C([C@@H](NC(CCCCCOP(OCCC#N)N(C(C)C)C(C)C)=O)C(C)(C)C)=O)[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C1)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 786.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL