Pomalidomide-piperazine-acetic acid is a functionalized cereblon ligand for development of pomalidomide-based ProTACs. Pomalidomide-piperazine-acetic acid allows rapid conjugation with amine linkers due to the presence of a carboxyl group via peptide coupling reactions.
MedKoo Cat#: 121163
Name: Pomalidomide-piperazine-acetic acid
CAS#: 2591180-39-9
Chemical Formula: C19H20N4O6
Exact Mass: 400.1383
Molecular Weight: 400.39
Elemental Analysis: C, 57.00; H, 5.04; N, 13.99; O, 23.98
The following data is based on the product molecular weight 400.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
