MedKoo Cat#: 121148 | Name: BCN-NHS
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BCN-NHS, also known as BCN-succinimidyl ester, is a ProTAC building block. BCN-NHS may be used to functionalize the primary amines of the lysine residue of recombinant elastin-like proteins (ELPs). It may also be used to synthesize bicyclononyne functionalized poly(ethylene glycol) polymer coatings with anti-fouling properties towards protein adhesion and cell adhesion for supramolecular ureidopyrimidinone (UPy) based materials.

Chemical Structure

BCN-NHS
BCN-NHS
CAS#1426827-79-3

Theoretical Analysis

MedKoo Cat#: 121148

Name: BCN-NHS

CAS#: 1426827-79-3

Chemical Formula: C15H17NO5

Exact Mass: 291.1107

Molecular Weight: 291.30

Elemental Analysis: C, 61.85; H, 5.88; N, 4.81; O, 27.46

Price and Availability

Size Price Availability Quantity
50mg USD 250.00 2 Weeks
100mg USD 450.00 2 Weeks
250mg USD 850.00 2 Weeks
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Related CAS #
1516551-46-4
Synonym
BCN-succinimidyl ester; BCN-NHS; endo-BCN-NHS carbonate; BCN-CO-NHS
IUPAC/Chemical Name
(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-succinimidyl carbonate
InChi Key
SKTDJYHCSCYLQU-ZSBIGDGJSA-N
InChi Code
1S/C15H17NO5/c17-13-7-8-14(18)16(13)21-15(19)20-9-12-10-5-3-1-2-4-6-11(10)12/h10-12H,3-9H2/t10-,11+,12-
SMILES Code
[H][C@@]12CCC#CCC[C@]1([H])[C@@H]2COC(ON3C(CCC3=O)=O)=O
Appearance
Solid
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 291.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL