Tinlorafenib, alos known as PF-07284890 and RRY-461, is an orally active and potent BRAF kinase inhibitor. Tinlorafenib demonstrates CNS penetration and can be used in the research of BRAF-associated malignant and benign tumors of the CNS as well as extracranial malignancies.
MedKoo Cat#: 121099
Name: Tinlorafenib
CAS#: 2573781-75-4
Chemical Formula: C19H19ClF2N4O3S
Exact Mass: 456.0834
Molecular Weight: 456.89
Elemental Analysis: C, 49.95; H, 4.19; Cl, 7.76; F, 8.32; N, 12.26; O, 10.51; S, 7.02
The following data is based on the product molecular weight 456.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
