MedKoo Cat#: 121052 | Name: UCM-1306

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UCM-1306 is an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson’s Disease.

Chemical Structure

UCM-1306
UCM-1306
CAS#2258608-80-7

Theoretical Analysis

MedKoo Cat#: 121052

Name: UCM-1306

CAS#: 2258608-80-7

Chemical Formula: C14H14FNO2S

Exact Mass: 279.0729

Molecular Weight: 279.33

Elemental Analysis: C, 60.20; H, 5.05; F, 6.80; N, 5.01; O, 11.46; S, 11.48

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
UCM-1306; UCM1306; UCM 1306
IUPAC/Chemical Name
(S)-(2'-(fluoromethoxy)-[1,1'-biphenyl]-4-yl)(imino)(methyl)-l6-sulfanone
InChi Key
VCSBOASGFYJGGT-IBGZPJMESA-N
InChi Code
InChI=1S/C14H14FNO2S/c1-19(16,17)12-8-6-11(7-9-12)13-4-2-3-5-14(13)18-10-15/h2-9,16H,10H2,1H3/t19-/m0/s1
SMILES Code
FCOC1=CC=CC=C1C2=CC=C([S@@](C)(=N)=O)C=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 279.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
García-Cárceles J, Vázquez-Villa H, Brea J, Ladron de Guevara-Miranda D, Cincilla G, Sánchez-Martínez M, Sánchez-Merino A, Algar S, Teresa de Los Frailes M, Roberts RS, Ballesteros JA, Rodríguez de Fonseca F, Benhamú B, Loza MI, López-Rodríguez ML. 2-(Fluoromethoxy)-4'-(S-methanesulfonimidoyl)-1,1'-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson's Disease. J Med Chem. 2022 Aug 31. doi: 10.1021/acs.jmedchem.2c00949. Epub ahead of print. PMID: 36044544.