MCS-0382 is a Photo-Activatable Ligand for Melatonin Receptor.. MCS-0382 showed the best uncaging and biological properties, with 250-fold increase in affinity and potency upon illumination. Generation of melatonin from MCS-0382 was further demonstrated by its ability to modulate the excitation of SCN neurons in rat brain slices. MCS-0382 is available to study melatonin effects in a temporally controlled manner in cellular and physiological settings.
MedKoo Cat#: 121040
Name: MCS-0382
CAS#: 2813865-88-0
Chemical Formula: C22H25N3O6
Exact Mass: 427.1743
Molecular Weight: 427.46
Elemental Analysis: C, 61.82; H, 5.90; N, 9.83; O, 22.46
The following data is based on the product molecular weight 427.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
