MedKoo Cat#: 208390 | Name: EML108

Description:

WARNING: This product is for research use only, not for human or veterinary use.

EML108 is a Type 1 inhibitor of PMRT. EM108 was able to prevent arginine methylation of cellular proteins in whole-cell assays, with activities comparable to AMI-1

Chemical Structure

EML108
EML108
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 208390

Name: EML108

CAS#: unknown

Chemical Formula: C23H16N2O7

Exact Mass: 432.0958

Molecular Weight: 432.39

Elemental Analysis: C, 63.89; H, 3.73; N, 6.48; O, 25.90

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
EML-108, eml108
IUPAC/Chemical Name
6,6'-(Carbonylbis(azanediyl))bis(4-hydroxy-2-naphthoic acid)
InChi Key
SIWVJBJPYHPOMC-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H16N2O7/c26-19-7-13(21(28)29)5-11-1-3-15(9-17(11)19)24-23(32)25-16-4-2-12-6-14(22(30)31)8-20(27)18(12)10-16/h1-10,26-27H,(H,28,29)(H,30,31)(H2,24,25,32)
SMILES Code
O=C(NC1=CC2=C(O)C=C(C(O)=O)C=C2C=C1)NC3=CC4=C(O)C=C(C(O)=O)C=C4C=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 432.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Giulia Iannelli, Ciro Milite, Nils Marechal, Vincent Cura, Luc Bonnefond, Nathalie Troffer-Charlier, Alessandra Feoli, Donatella Rescigno, Yalong Wang, Alessandra Cipriano, Monica Viviano, Mark T. Bedford, Jean Cavarelli, Sabrina Castellano, and Gianluca Sbardella Journal of Medicinal Chemistry Article ASAP DOI: 10.1021/acs.jmedchem.2c00252