MK-0159 is a CD38 enzymatic inhibitor. Mice treated with MK-0159 show strong protection from myocardial damage upon cardiac I/R injury compared to those treated with NAD+ precursors (nicotinamide riboside) or another CD38 inhibitor.
MedKoo Cat#: 121008
Name: MK-0159
CAS#: 2641484-61-7
Chemical Formula: C21H26N4O3S
Exact Mass: 414.1726
Molecular Weight: 414.52
Elemental Analysis: C, 60.85; H, 6.32; N, 13.52; O, 11.58; S, 7.73
The following data is based on the product molecular weight 414.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
