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MedKoo Cat#: 208354 | Name: LTI6426

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PDI inhibitor LTI6426 enhances panobinostat efficacy in preclinical models of multiple myeloma

Chemical Structure

LTI6426
LTI6426
CAS# 2285446-67-3

Theoretical Analysis

MedKoo Cat#: 208354

Name: LTI6426

CAS#: 2285446-67-3

Chemical Formula: C19H23F3O2

Exact Mass: 340.1650

Molecular Weight: 340.39

Elemental Analysis: C, 67.04; H, 6.81; F, 16.74; O, 9.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LT-I6426, L-T-I-6426, E64FC26
IUPAC/Chemical Name
(E)-1-Nonylidene-3-(trifluoromethyl)-1H- indene-5,6-diol
InChi Key
OWYMWLCFHDHVAH-UKTHLTGXSA-N
InChi Code
InChI=1S/C19H23F3O2/c1-2-3-4-5-6-7-8-9-13-10-16(19(20,21)22)15-12-18(24)17(23)11-14(13)15/h9-12,23-24H,2-8H2,1H3/b13-9+
SMILES Code
OC1=CC2=C(/C(C=C2C(F)(F)F)=C/CCCCCCCC)C=C1O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 340.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Robinson RM, Basar AP, Reyes L, Duncan RM, Li H, Dolloff NG. PDI inhibitor LTI6426 enhances panobinostat efficacy in preclinical models of multiple myeloma. Cancer Chemother Pharmacol. 2022 May;89(5):643-653. doi: 10.1007/s00280-022-04425-3. Epub 2022 Apr 5. PMID: 35381875; PMCID: PMC9054865.

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Delanterone

Delanterone