NHWD-870 is a BET inhibitor that is more potent than three major clinical stage BET inhibitors BMS-986158, OTX-015, and GSK-525762. NHWD-870 causes tumor shrinkage or significantly suppresses tumor growth in nine xenograft or syngeneic models.
MedKoo Cat#: 208307
Name: NHWD-870
CAS#: 2115742-03-3
Chemical Formula: C29H29N7O
Exact Mass: 491.2434
Molecular Weight: 491.60
Elemental Analysis: C, 70.85; H, 5.95; N, 19.94; O, 3.25
The following data is based on the product molecular weight 491.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
