CHD1Li 6.11 is an inhibitor of Chromodomain helicase DNA-binding protein 1 like (CHD1L), which is an oncogene implicated in tumor progression, multidrug resistance, and metastasis in many types of cancer. CHD1Li 6.11 proved to be an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties.
MedKoo Cat#: 208296
Name: CHD1Li 6.11
CAS#: 2716890-91-2
Chemical Formula: C21H22BrN5OS
Exact Mass: 471.0728
Molecular Weight: 472.41
Elemental Analysis: C, 53.39; H, 4.69; Br, 16.91; N, 14.83; O, 3.39; S, 6.79
The following data is based on the product molecular weight 472.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
