MedKoo Cat#: 556120 | Name: BMS-905
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BMS-905 is a Dual Antagonist of Toll-like Receptors 7 and 8 (TLR7/8)

Chemical Structure

BMS-905
BMS-905
CAS#2205846-49-5

Theoretical Analysis

MedKoo Cat#: 556120

Name: BMS-905

CAS#: 2205846-49-5

Chemical Formula: C23H29N3

Exact Mass: 347.2361

Molecular Weight: 347.51

Elemental Analysis: C, 79.50; H, 8.41; N, 12.09

Price and Availability

Size Price Availability Quantity
50mg USD 1,250.00 2 Weeks
100mg USD 1,850.00 2 Weeks
200mg USD 2,650.00 2 Weeks
500mg USD 3,650.00 2 Weeks
1g USD 5,650.00 2 Weeks
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Related CAS #
No Data
Synonym
BMS-905; BMS 905; BMS905;
IUPAC/Chemical Name
2-(2,6-Dimethylpyridin-4-yl)-5-piperidin-4-yl-3-propan-2-yl-1H-indole
InChi Key
XSXCQWXAFRASGU-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H29N3/c1-14(2)22-20-13-18(17-7-9-24-10-8-17)5-6-21(20)26-23(22)19-11-15(3)25-16(4)12-19/h5-6,11-14,17,24,26H,7-10H2,1-4H3
SMILES Code
CC(C1=C(C2=CC(C)=NC(C)=C2)NC3=C1C=C(C4CCNCC4)C=C3)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 347.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Sreekantha RK, Mussari CP, Dodd DS, Pasunoori L, Hegde S, Posy SL, Critton D, Ruepp S, Subramanian M, Salter-Cid LM, Tagore DM, Sarodaya S, Dudhgaonkar S, Poss MA, Schieven GL, Carter PH, Macor JE, Dyckman AJ. Identification of 2-Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8). ACS Med Chem Lett. 2022 Apr 25;13(5):812-818. doi: 10.1021/acsmedchemlett.2c00049. PMID: 35586440; PMCID: PMC9109266.