Related CAS #
62745-67-9 (alternate)
IUPAC/Chemical Name
2,5-Cyclohexadien-1-one, 2-hydroxy-5-methoxy-4-(3-phenyl-2-propenylidene)-, (E,E)-
InChi Key
LUZUAYAKZLCOCQ-GKPGWJKISA-N
InChi Code
InChI=1S/C16H14O3/c1-19-16-11-15(18)14(17)10-13(16)9-5-8-12-6-3-2-4-7-12/h2-11,17H,1H3/b8-5+,13-9-
SMILES Code
COC1=CC(=O)C(=C/C/1=C/C=C/c2ccccc2)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
254.28
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Teng J, Lashgari G, Tabet EI, Tannous BA. The natural compound obtusaquinone targets pediatric high-grade gliomas through ROS-mediated ER stress. Neurooncol Adv. 2020 Aug 27;2(1):vdaa106. doi: 10.1093/noajnl/vdaa106. PMID: 33134921; PMCID: PMC7592425.
2: Badr CE, da Hora CC, Kirov AB, Tabet E, Amante R, Maksoud S, Nibbs AE, Fitzsimons E, Boukhali M, Chen JW, Chiu NHL, Nakano I, Haas W, Mazitschek R, Tannous BA. Obtusaquinone: A Cysteine-Modifying Compound That Targets Keap1 for Degradation. ACS Chem Biol. 2020 Jun 19;15(6):1445-1454. doi: 10.1021/acschembio.0c00104. Epub 2020 May 8. PMID: 32338864; PMCID: PMC7995447.
3: Badr CE, Van Hoppe S, Dumbuya H, Tjon-Kon-Fat LA, Tannous BA. Targeting cancer cells with the natural compound obtusaquinone. J Natl Cancer Inst. 2013 May 1;105(9):643-53. doi: 10.1093/jnci/djt037. Epub 2013 Mar 11. PMID: 23479453; PMCID: PMC3691947.
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6: Guanche AD, Prawer S. Generalized eczematous contact dermatitis from cocobolo wood. Am J Contact Dermat. 2003 Jun;14(2):90-2. PMID: 14749027.
7: Hausen BM. Allergic contact dermatitis from a wooden necklace. Am J Contact Dermat. 1997 Sep;8(3):185-7. PMID: 9249295.
8: Rackett SC, Zug KA. Contact dermatitis to multiple exotic woods. Am J Contact Dermat. 1997 Jun;8(2):114-7. PMID: 9153334.
9: Hausen BM, Münster G. Cocobolo-Holz, ein vergessenes Ekzematogen? Neuere Erkenntnisse über das Hauptallergen des Cocobolo-Holzes (Dalbergia sp.) [Cocobolo wood, a forgotten eczematogen? Recent findings on the skin allergen of cocobolo wood (Dalbergia sp.)]. Derm Beruf Umwelt. 1983;31(4):110-7. German. PMID: 6226513.
