MedKoo Cat#: 112138 | Name: Compound C108
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation.

Chemical Structure

Compound C108
CAS#15533-09-2

Theoretical Analysis

MedKoo Cat#: 112138

Name: Compound C108

CAS#: 15533-09-2

Chemical Formula: C15H14N2O3

Exact Mass: 270.1004

Molecular Weight: 270.29

Elemental Analysis: C, 66.66; H, 5.22; N, 10.36; O, 17.76

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
Compound C108
IUPAC/Chemical Name
(E)-2-hydroxy-N'-(1-(2-hydroxyphenyl)ethylidene)benzohydrazide
InChi Key
LQGMBUGEAAGJKW-MHWRWJLKSA-N
InChi Code
InChI=1S/C15H14N2O3/c1-10(11-6-2-4-8-13(11)18)16-17-15(20)12-7-3-5-9-14(12)19/h2-9,18-19H,1H3,(H,17,20)/b16-10+
SMILES Code
OC1=C(C=CC=C1)/C(C)=N/NC(C2=C(C=CC=C2)O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM comments
Solubility
DMF 1.0 3.70
DMSO 1.0 3.70
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 270.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zheng Y, Wu J, Deng R, Lin C, Huang Y, Yang X, Wang C, Yang M, He Y, Lu J, Su X, Yan Q, Zhu Y, Guan X, Li Y, Yun J. G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript. Oncogene. 2022 Jan;41(4):515-526. doi: 10.1038/s41388-021-02073-0. PMID: 34782720; PMCID: PMC8782723. 2: Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn LL, Jain RK, Garkavtsev I. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1033-1038. doi: 10.1073/pnas.1525387114. Epub 2017 Jan 17. PMID: 28096337; PMCID: PMC5293063.