Macbecin I is a benzoquinone ansamycin antibiotic that binds to and inhibits heat shock protein 90 (Hsp90) in vitro (IC50 = 2 mM for Hsp90 ATPase activity) and the growth of 38 cancer cell lines (mean IC50 = 0.4 mM).
MedKoo Cat#: 112130
Name: Macbecin I
CAS#: 73341-72-7
Chemical Formula: C30H42N2O8
Exact Mass: 558.2941
Molecular Weight: 558.67
Elemental Analysis: C, 64.50; H, 7.58; N, 5.01; O, 22.91
The following data is based on the product molecular weight 558.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
